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T0993 |
Methoxamine hydrochloride
|
Methoxamine HCl |
Adrenergic Receptor
|
|
Methoxamine hydrochloride (Methoxamine HCl) is an alpha-1 adrenergic agonist that causes prolonged peripheral VASOCONSTRICTION. |
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T22459 |
Xanthinol Nicotinate
|
Angioamin,Complamin |
Others
|
|
Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy. |
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T1275 |
Phentolamine mesylate
|
Phentolamine methanesulfonate,Phentolamine mesilate |
Adrenergic Receptor
|
|
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS... |
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T0712 |
Suloctidil
|
|
ATPase
,
Platelet aggregation
|
|
Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. |
|
T9881 |
Benzoquinamide hydrochloride
|
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride |
Others
|
|
Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the incre... |
|
T0806 |
Flunarizine dihydrochloride
|
Flunarizine 2HCl,KW-3149,R14950 |
Calcium Channel
,
Dopamine Receptor
,
Sodium Channel
|
|
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of mig... |
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T0957 |
Isradipine
|
PN 200-110 |
Calcium Channel
,
Autophagy
|
|
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc... |
|
T1081 |
Naftidrofuryl oxalate
|
Nafronyl oxalate,Nafronyl oxalate salt |
5-HT Receptor
|
|
Naftidrofuryl oxalate (Nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. It may also be an ant... |
|
T1439 |
Lacidipine
|
SN-305,GX-1048,GR-43659X |
Apoptosis
,
Calcium Channel
,
Reactive Oxygen Species
|
|
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... |
|
T0182L2 |
(±) Clopidogrel hydrogen sulfate
|
Plavix,Clopidogrel hydrogen sulfate,Iscover |
P2Y Receptor
|
|
(±) Clopidogrel hydrogen sulfate (Iscover) , an antiplatelet agent pharmacologically and structurally analogous to ticlopidine, is used to inhibit blood clots in various conditions such as cerebrovascular disease, periph... |
|
TP1918L1 |
Lys-[Des-Arg9]Bradykinin acetate
|
Lys-[Des-Arg9]Bradykinin acetate (71800-36-7 free base) |
Bradykinin Receptor
|
|
Lys-[Des-Arg9]Bradykinin acetate is an endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces p... |
|
TP1918L |
Lys-[Des-Arg9]Bradykinin,TFA
|
Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa) |
Bradykinin Receptor
|
|
Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripher... |
|
T1050 |
Prazosin hydrochloride
|
Prazosin hydrochloride,Prazosin HCl,cp-12299-1,Peripress,Vasoflex,Minipress |
Potassium Channel
,
MRP
,
Adrenergic Receptor
,
ABC
,
Autophagy
|
|
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic ... |
|
T11043 |
Dihydroergocristine mesylate
|
DHEC (mesylate) |
Beta Amyloid
|
|
Dihydroergocristine mesylate (DHEC (mesylate))(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as the for the symptomatic treatment of mental deterioration associated with cerebro... |
|
T0712L |
Suloctidil HCl
|
|
|
|
Suloctidil HCl is a peripheral vascular dilator. |
|
T25848 |
Naftidrofuryl
|
|
|
|
Naftidrofuryl is used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be spasmolytic. |
|
T0368L |
Cinepazide
|
Brendil,MD67350,Vasodistal,Cinepazide free base,MD-67350,MD 67350,NSC 291562 |
|
|
Cinepazide is a vasodilator used for the treatment of cardiovascular, cerebrovascular, and peripheral vascular diseases. Cinepazide acts as a potentiator of adenosine A2 receptors. |
|
T5391L |
Bepridil free base
|
CERM1978,CERM 1978,Bepadin,CERM-1978,Angopril |
|
|
Bepridil is a class IV anti-arrhythmic agent and calcium antagonist. Bepridil hydrochloride blocks calcium entry through membranous calcium channels of coronary and peripheral vascular smooth muscle, thereby dilating cor... |
|
T69239 |
Nylidrin
|
|
|
|
Nylidrin is a beta-adrenergic agonist. Nylidrin causes peripheral vasodilation, a positive inotropic effect, and increased gastric volume of gastric juice. It is used in the treatment of peripheral vascular disorders and... |
|
T21392 |
Flunarizine
|
Flunarizinum,Flunarizin,Sibelium,Flunarizina,R-14950 |
|
|
Flunarizine is a non-selective calcium entry blocker and a histamine H1 receptor blocker. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, a... |
|
T32833 |
Lobeline, (+)-
|
(+)-Lobeline |
|
|
Lobeline, (+)- is an alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent. It has been proposed for a variety of therapeutic uses including in respiratory disorders, periphe... |
|
T69303 |
Isoxsuprine Free Base
|
|
|
|
Isoxsuprine Free Base is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle. Its vasodilating actions are greater on the arteries supplying skeletal muscle than on those supplyi... |
|
T15560 |
Iloprost
|
ZK 36374,Ciloprost |
Others
|
|
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost commonly employed in the treatment of peripheral vascular disease and also indicated in the treatment of patients affected by systemic sclerosis (SSc) in th... |
|
T68825 |
Doxazosin HCl
|
|
|
|
Doxazosin HCl is the salt form of Doxazosin Free Base which acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally releas... |
|
TP1918 |
Lys-[Des-Arg9]Bradykinin
|
|
|
|
Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. ... |
|
T68639 |
Ciprostene (free base)
|
|
|
|
Ciprostene (free base) is a synthetic, chemically stable analog of prostacyclin (PGI2). In animal models, administration of ciprostene resulted in dose-dependent hypotension, tachycardia, and inhibition of ex vivo ADP-in... |
|
T29907 |
Alprostadil sodium
|
PGE1 sodium salt,Prostaglandin E1 sodium |
|
|
Alprostadil sodium is a prostaglandin receptor ligand with Ki values of 36, 10, 1.1, 2.1, and 33 nM for EP1, EP2, EP3, EP4, and IP, respectively, in mice.It induces vasodilatation and inhibits platelet aggregation, and i... |
|
T63035 |
Izilendustat hydrochloride
|
|
|
|
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase that stabilizes hypoxia-inducible factor-1 alpha (HIF-1α) and hypoxia-inducible factor-2 (HIF-2). Potential for HIF-1α-related diseases (including ... |
|
T17231 |
Vicagrel
|
|
Others
|
|
Vicagrel is an effective, orally active antiplatelet compound that enhances the inhibitory effect of aspirin on platelet aggregation and thrombosis in rodents by irreversibly inhibiting P2Y12 receptors and reducing metab... |
|
T83899 |
N-didesmethyl Loperamide
|
R 21345 |
|
|
N-didesmethyl Loperamide, an active metabolite of the peripheral μ1-opioid receptor agonist loperamide, impedes electrically induced contractions in isolated guinea pig myenteric plexus (IC50 = 370 nM) and enhances the s... |
|
T38128 |
Leukotriene D4
|
Leukotriene D4 MaxSpec® Standard,LTD4 |
|
|
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4... |
|
T35604 |
Osteocalcin (1-49) (human) (trifluoroacetate salt)
|
|
|
|
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D ... |
